Randomised control trial (RCT) is a study in which people are allocated at random (by chance alone) to receive one of several clinical interventions. One of these interventions is the standard of comparison or control.

Design of a randomized control trial (RCT). What are the types of RCT? What is blinding? April 2016

Randomised control trial (RCT)^​1,2​

• Experimental, best study design
• Cross over of patients can be done – further increases the quality of the study
• Target population should be identified before conducting the study – refers to the population on whom the results of the study will be generalised
• The study should include a part of this target population itself
• Ethics committee approval before the study – mandatory
• Written informed consent, in a language which patient can understand, taken before the study – mandatory

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