Inverted papilloma -case Report

Last modified: May 30, 2021
Estimated reading time: 3 min

Definition of Inverted Papilloma 

Inverted papilloma is a benign, epithelial neoplasm originating from the Schneiderian membrane of the noseand paranasal sinuses. It usually arises from the lateral nasal wall, in the middle meatus, often extending to the ethmoid and maxillary sinuses. In advanced cases, extension into all of the ipsilateral paranasal sinuses may occur, whereas intracranial growth and Dura penetration are rare.

Their characteristic inverted mucosal surface extending into the stroma of the papilloma leads to the term inverted for these lesions.

They occur more frequently in men (3:1) and have an incidence of approximately 1 per 100,000 population.

Although benign, they behave in a locally aggressive manner, requiring wide local excision if recurrence is to be prevented. Malignant transformation can occur in up to 10 per cent of lesions but is typically reported as occurring in approximately 2 per cent. The aetiology remains unclear, and the reasons for malignant transformation similarly are unknown.

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